In Deployment


The management of complex, contaminated abdominal wounds remains largely dependent upon the experience and judgment of the surgeon. This may result in either the premature closure of abdominal wounds destined for clinical failure or performing additional procedures on wounds well beyond the window necessary for successful closure. There is therefore a need for a standardized process to determine the best method for achieving expedient and successful definitive closure of abdominal fascia. We are designing a Clinical Decision Support tool that will provide the necessary objective criteria for predicting successful abdominal closure after damage control laparotomy. This could potentially help us achieve delayed fascial closure during the same hospital admission when it can be accomplished safely, while avoiding the complications of multiple unsuccessful attempts to do the same. This might also optimize the chance of a successful planned staged ventral hernia. The ultimate goal is to improve outcomes while reducing costs for hospitals and victims of traumatic abdominal injury.


Blast injuries and other combat-associated wounds present unique challenges to healthcare enterprises. We found that a comprehensive biological assessment, coupled with advanced mathematical techniques, can be used to generate a predictive model that may help surgeons improve outcomes by minimizing wound-related complications. This translates to shorter hospital stays, quicker rehabilitation, and lower costs. We then distilled the prognostic information into a Clinical Decision Support tool called WOUNDx™, which uses common inflammatory markers coupled with clinical observations to estimate the likelihood of wound failure in complex wounds. This highly predictive algorithm can help surgeons identify when to close or otherwise cover wounds in high risk military and civilian populations.